Overdosage of cholestyramine resin is noted in a patient taking a hundred and fifty% of the utmost advisable day by day dosage for your duration of numerous weeks. No sick consequences have been claimed.
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Occasional calcified content has been observed while in the biliary tree, which include calcification in the gallbladder, in clients to whom cholestyramine resin has actually been supplied. However, this may be a manifestation on the liver sickness and not drug similar.
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Nevertheless, in view of The reality that cholestyramine resin is confined for the GI tract and never absorbed and in light of your animal experiments referred to previously mentioned, a six-year publish-demo observe-up of the LRC-CPPT5 patient populace has actually been accomplished (a total of thirteen.4 decades of in-demo in addition put up-demo abide by-up) and revealed no sizeable variation while in the incidence of result in-particular mortality or cancer morbidity between cholestyramine and placebo taken care of patients.
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